Research Articles
Unveiling the Hidden Resistome: Advanced Strategies for Detecting Low-Abundance Antibiotic Resistance Genes
The detection of low-abundance antibiotic resistance genes (ARGs) is a critical frontier in combating the global antimicrobial resistance (AMR) crisis.
Beyond the Known: Strategies to Overcome Database Selection Bias in Resistome Analysis
Antimicrobial resistance (AMR) poses a critical global health threat, making accurate resistome characterization essential.
Beyond Best Hits: Advanced Strategies to Reduce False Positives in Antibiotic Resistance Gene Classification
Accurate identification of antibiotic resistance genes (ARGs) is critical for combating the global antimicrobial resistance crisis.
Overcoming PCR Inhibition in Environmental Antibiotic Resistance Gene Detection: Strategies for Robust Molecular Surveillance
Accurate detection of antibiotic resistance genes (ARGs) in environmental samples via PCR is critical for One Health surveillance but is frequently compromised by potent PCR inhibitors.
A Modern Bioinformatic Workflow for Comparative Resistome Analysis: From Raw Data to Actionable Insights
This article provides a comprehensive guide for researchers and bioinformaticians on establishing a robust bioinformatic workflow for comparative resistome analysis.
Mastering AMRFinderPlus: A Comprehensive Guide to Parameters for Effective Antimicrobial Resistance Gene Screening
This article provides researchers, scientists, and drug development professionals with a complete guide to leveraging NCBI's AMRFinderPlus for comprehensive antimicrobial resistance gene (ARG) detection.
CARD vs. ResFinder: A Comprehensive Comparison for Antimicrobial Resistance Gene Detection
This article provides a systematic comparison of the Comprehensive Antibiotic Resistance Database (CARD) and ResFinder, two leading resources for identifying antibiotic resistance genes (ARGs) from genomic and metagenomic data.
Profiling the Antibiotic Resistome in Clinical Isolates: Molecular Insights, Surveillance Strategies, and Therapeutic Frontiers
The profiling of the antibiotic resistome in clinical isolates has become a cornerstone in the global fight against antimicrobial resistance.
Unveiling the Resistome: Advanced Strategies for Discovering Antibiotic Resistance Genes in Complex Microbial Communities
The rapid proliferation of antibiotic resistance genes (ARGs) in environmental and clinical settings represents a critical global health challenge.
Mobile Genetic Elements: The Unseen Drivers of the Antibiotic Resistance Crisis
This article provides a comprehensive exploration of the pivotal role mobile genetic elements (MGEs) play in the global spread of antimicrobial resistance (AMR).